Oligo Modification By Property
June 18, 2026 / June 19, 2026 by Dawn Lam
Introduction to Antisense Oligos (ASOs) Antisense Oligonucleotides (ASOs) are fairly short oligonucleotides, typically 15-30 nucleotides in length, which are composed of either DNA, RNA or a mixture of both. The RNA nucleotides are invariably ribonucleoside analogs that lack a 2’-hydroxyl but still favor a 3’-endo sugar pucker such that the ASO-target duplex adopts a tighter, […]
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