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Company Overview

At Synoligo, our mission is to empower scientific communities on their research to advance human health by unleashing the power of oligo customization. We manufacture complex and highly modified oligonucleotides for the academic, biotech start-up, and large pharmaceutical communities, delivering high-quality, cost-effective custom oligos at every scale.

Who We Are

A Contract Research & Development Partner Built For Complex Oligos

Synoligo Biotechnologies, based in Morrisville, NC, is a Contract Research and Development Organization (CRDO) specializing in complex and highly modified oligonucleotides. We provide in silico design, custom synthesis, and lead candidate screening, supporting programs from early discovery through pre-clinical development as a true one stop oligo partner for research, diagnostic, and therapeutic innovation.

SynOptuma oligo vials
100+
Years of oligo synthesis expertise
from leadership team
100%
U.S.-based operations
No Scale Guesswork
Priced on delivered yield,
not synthesis scale
What We Cover

Oligos For Drug Discovery Program

Synoligo service areas across basic research, discovery, pre-clinical, and bioanalytical analysis
Popular Services

Where Programs Rely On Us Most

Therapeutics

End-To-End Workflow

Design to preclinical: in-silico design, synthesis, purification, scale-up.

Therapeutics

Oligo Conjugation

Conjugates: antibody, peptide, protein, small molecule, custom payloads.

Therapeutics

Rare Disease Oligos

Bespoke programs: siRNA, ASO and PMO for small patient populations.

Diagnostics

Diagnostic Probes

Clinical lab testing: specialized probes, primers, and controls.

Let's Advance Your Oligo Program Together

Talk to a Synoligo scientist about your project, from pilot studies to preclinical scale-up.

Our Foundation

Core Values That Guide Our Decisions And Actions

Integrity

We uphold the highest ethical standards in all aspects of our work, from the quality of our products to the way we treat our team members.

Trust

We build and maintain trust with clients, employees, and partners through open communication, transparency, and consistently delivering on our promises.

Collaboration

We encourage idea sharing and teamwork to harness the power of innovation from the collective expertise of diverse minds.

Commitment

We are committed to delivering the best possible services and products for the communities we serve. Our pursuit of excellence is driven by our commitment.

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