Oligo Modification By Application RNA Modification
February 13, 2025 / February 27, 2025 by Dawn Lam
A recent paper by Wave Life Sciences1 describes a new application of isouridine (N3U) for improving the efficiency of ADAR-assisted editing of mRNA in a disease-relevant target. Background ADARs (Adenosine Deaminase Acting on RNA) are endogenous enzymes that are found in all vertebrates. In humans ADAR1 and ADAR2 bind dsRNA and perform A-to-I edits at […]
Read more »
Tagged
Oligo Modification By Application Spatial Transcriptomics
October 11, 2024 / February 5, 2025 by Dawn Lam
What is Spatial Transcriptomics? Spatial transcriptomics is a cutting-edge technology that allows researchers to study gene expression profiles of cells while maintaining their location within a tissue. This method has become popular in fields like oncology, neurobiology, and developmental biology due to its ability to map gene expression at single-cell resolution. By preserving tissue architecture, […]
CRISPR Oligo Modification By Application
June 5, 2024 / February 5, 2025 by Dawn Lam
What is CRISPR Technology? CRISPR/CasX Technology (Clustered Regularly Interspaced Short Palindromic Repeats), derived from bacteria, has been a cornerstone of genetic engineering in the therapeutic industry for decades. The technology is versatile with its application, spanning across various fields, from agriculture to medicine, and enabling scientists to modify DNA sequences with remarkable accuracy. The most […]
Get access to technical content, promotions, upcoming events and press release.
