Research Oligos
Custom Oligo Synthesis Made Simple, Reliable, and Ready for Research.
Overview
Oligonucleotides play an essential and versatile role in various research areas. Their unique properties allow for customization of length and sequence, catering to specific research needs. Synoligo specializes in providing a comprehensive suite of oligo synthesis options for both DNA and RNA. Our scalable solutions empower customers to delve into fundamental research acrossdiverse applications such as immunoassays, cloning/PCR, antisense experiments, gene editing, and more.
Stages We Cover
Explore our comprehensive solutions tailored for the development, manufacturing and testing of oligonucleotides from research to preclinical stage.
Features & Benefits
Adaptable
Synthesis
Expertise in common and novel modifications
Unmatched
Support
Ensure a personalized experience
Convenient
Ordering
Online form, scheduled meeting, email or phone
Fast
Delivery
Reliable turnaround time
Oligo Architecture
- Ultralong single-stranded
- Duplex
- Triplex
- G-quadruplex
- Branched
- Dendrimeric
- Circular
- Aptamer
Inducible Strand Cleavage
- Photo-induced
- Enzymatic
- Redox
Inducible Strand Ligation
- Trans-cyclooctene/Tetrazine
- Thiophosphate/Dabsyl
- Thiophosphate/Iodo
- Thiol/Maleimide
- DBCO/Azide
- Alkyne/Azide
Conjugation & Labeling
- CCPs (Cell-penetrating Peptides)
- NLSs (Nuclear Localization Signals)
- TAT Peptide
- Antibodies
- Peptides
- Fluorescent dyes
- Time-gated Lanthanides
- Redox labels
Epigenetic Markers
- N6-Methyladenosine
- 5-Hydroxymethylcytosine
- N4-acetylcytosine
- 5-formylcytosine
- N1-methyladenosine
- Pseudouridine
Gene Expression Modulation
- siRNA (RNAi for knockdown)
- saRNA (RNAa for activation)
- sgRNA (CRISPR - Cas system)
- ASO (Antisense Oligonucleotides)
- SSO (Splice-switching Oligomers)
Sugar Modifications
- LNAs (Locked Nucleic Acids)
- cET (Constrained Ethyl Nucleosides)
- 2'-O-Methyl
- 2'-MOE (2'-Methoxyethyl)
Backbone Modifications
- PMOs
- PNAs
- PN1 (Phosphoryl guanidine)
- MsPA (Mesyl phosphoramidate)
- PS (Phosphorothioate)
- Stereopure backbone modifications
Other Modifications
Leverage over 700 available modifications to customize your oligo for optimal performance.
What We Offer
We combine technical excellence with reliability to help you achieve research success.
Deeper Knowledge
Explore Our Blog for Advanced Oligo Topics
Cleavable Linkers (AOC vs ADC)
Choosing Linkers for Antibody-Oligonucleotide Conjugates (AOCs) versus for Antibody-Drug Conjugates (ADCs)
Read More5’ Triphosphate Oligonucleotides
What are 5’ triphosphate oligonucleotides and how are they being used?
Read MoreUltra-Long Oligos
What is CRISPR Technology? What is the role of gRNA/sgRNA in the CRISPR system?
Read MoreNuclease Resistance
What are some current nuclease resistance modifications that are being used?
Read MoreBackbone Modification - Mesyl Phosphoramidate
What are antisense oligonucleotides (ASOs)? Why is mesyl phosphoramidate modification being used?
Read MoreApplications of Oligos
With decades of experience, our expert team specializes in manufacturing oligos tailored to diverse scientific applications, ensuring your specific needs are met.
Research Oligos
Extensive list of customization allows researchers to achieve their research goals.
- Branched/dendrimer
- Circular DNA/RNA
- Ultra-long oligos (150–200nt)
- DNA-encoded library (DEL)
Diagnostic Oligos
Broad selection of various dyes and probes.
- Primers PCR/qPCR
- FISH/MERFISH Probes
- FRET Probes
- NGS Adapters
- Molecular Beacons
Therapeutic Oligos
Guarantee ultra low endotoxin even for lipid modified oligo.
- Antisense
- Immunostimulatory
- mi-/sa-/siRNA
- Aptamer
- CRISPR gRNA
Order Now!
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Skip the back-and-forth emailing. Get your order processed immediately using a credit card or your standard Purchase Order (PO).
