Backbone Oligo Modification by Type

Stereopure Oligonucleotides with Different Backbone Chemistries

November 22, 2024 / February 2, 2025 by Dawn Lam

Check out our updated section below! What are antisense oligonucleotides (ASOs)? Antisense oligonucleotides (ASOs) are short nucleic acids designed to bind to specific RNA sequences, thereby inhibiting, reducing, restoring, or modifying the expression of target RNA. Over the past two decades, this method of gene silencing at the posttranscriptional stage has become increasingly popular as […]

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Backbone Oligo Modification by Type

Mesyl Phosphoramidate Modification

May 6, 2024 / February 2, 2025 by Dawn Lam

Check out our updated section below! What are antisense oligonucleotides (ASOs)? Antisense oligonucleotides (ASOs) are short nucleic acids designed to bind to specific RNA sequences, thereby inhibiting, reducing, restoring, or modifying the expression of target RNA. Over the past two decades, this method of gene silencing at the posttranscriptional stage has become increasingly popular as […]

Read more »