Diagnostic Oligos

We specialize in synthesizing high-quality oligonucleotides, primers, and probes across the full spectrum of molecular diagnostics.

What We Offer

Overview

Oligonucleotides have emerged as the dominant player in the molecular diagnostics field. At Synoligo, we understand the critical need for high-quality products that yield reliable and reproducible results when testing valuable samples. That's why leading diagnostic companies partner with us in their early design stages, relying on Synoligo's consistency in producing their custom oligonucleotides, probes, and primers.

Areas We Cover

Our team ensures every custom oligo, primer, and probe meets therapeutic-quality standards, giving you the confidence you need for critical testing.

Confidence you need for critical testing.

Features & Benefits

Diverse Probes
& Primers

Guaranteed
Product Quality

Reliability &
Scalability

Customized
Processes

Probes

Labeled and Modified Probes

Biotin
Digoxigenin
Constrained alkynes (e.g. DBCO, BCN, TCO)
Azide
Amine
Thiol
Redox (e.g.ferrocene)
Fluorophores (e.g. FAM™, HEX™, ROX™ etc.)
Quenchers (e.g Black Dark Quencher (BDQ) etc.)
Quantum dots
Lanthanide luminescent labels
PNA probes
Custom probes

Dual-Labeled Probes

Standard qPCR/SNP genotyping probes
Double-quenched probes
Probe with hairpin structure (Molecular Beacon, Scorpion™)
Time-gated detection probes
Probes with custom labels and dyes

Hepatic and Extrahepatic Delivery

Propyne modified
LNA modified
BNA modified

Primers

Standard DNA Primers

Adapter Primers

Blocking Primers

3'-Spacer
3'-Inverted
3'-Dideoxy
3'-Amino
3'-Phosphorylation

Modified Primers

PTO (phosphorothioate)
3'-Exo blocking primers

Spatial Transcriptomics

FISH

smFISH
MERFISH

RNAScope™

High-quality probes designed for exceptional sensitivity and single-cell resolution in spatial gene expression studies.

Nanostring GeoMX®

Custom probes optimized for high-plex spatial profiling, enabling precise gene and protein expression analysis across complex tissue samples.

Other

Modified Oligos

Modification on the 5', 3' or internal location
Modifications on the base, sugar ring, or backbone

Custom Formulation

NGS grade
Oligo pools
Wobble/Degenerate
Formulation buffer
OEM
Stamping

Analytical Testing/Validation

Comprehensive services designed to meet rigorous quality and regulatory standards.

What We Offer

Bringing Therapeutic Quality to Diagnostic Oligos.

Our oligos are versatile and suitable for various applications including PCR, sequencing, cloning, gene detection, and assays. In addition, we offer a diverse range of probes and primers for you to choose from.

Take advantage of our 650+ modification modifiers to tailor the properties of your oligo.

Applications of Oligos

With decades of experience, our expert team specializes in manufacturing oligos tailored to diverse scientific applications, ensuring your specific needs are met.

Research Oligos

Extensive list of customization allows researchers to achieve their research goals.

Branched/dendrimer
Circular DNA/RNA
Ultra-long oligos (150–200nt)
DNA-encoded library (DEL)