5' Terminal Caps Oligo Modification by Type
September 18, 2024 / February 19, 2025 by Dawn Lam
What are 5′ triphosphate oligonucleotides and how are they being used? 5′ triphosphate (5′-PPP) oligonucleotides are short strands of nucleic acids with a triphosphate group attached to their 5′ end (Image 1). This 5′-triphosphate plays crucial roles in biological processes, particularly in RNA biology. Incorporating 5′-PPP into RNA or DNA oligos enables a variety of […]
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