SynOligo delivers where others fall short.  All of the “big box” oligo houses can deliver PCR primers and standard modification DNA but fall short when it comes to truly custom oligos requiring nonstandard processing.  It is this custom space where SynOligo standouts.  My company has been ordering custom Oligos for 15+ years.  We have witnessed the demise through acquisition of the custom oligo houses that truly understand DNA synthesis including the “whys” and “gotchas” of oligonucleotide synthesis. Thankfully SynOligo has come on the scene with a team of highly experienced chemists that understand the ins and outs of oligonucleotide synthesis and what it means to deliver on time as promised.

We have been working with Synoligo for the past 6 months and they provide top quality services for custom synthesis of oligonucleotides and their conjugates. Synoligo set themselves apart first by being able to reach tight specifications for cleanliness of oligos designed to be used in challenging routes of administration and provide fast turn-around time without compromising on quality. Synoligo is also a great partner in method development for challenging targets and provides close to real time feedback on technical challenges while keeping an open mind and trying and providing actionable solutions. Synoligo has also been flexible with the different specifications and requirements for our oligos and their response time is typically less than a day making them a very reactive and efficient partner. We look forward to keep working with Synoligo in the future!

SynOligo team provides unprecedented services that exceed my expectations in all aspects. Superb customer service with consistently quick email responses to questions and quotations. Fast turnaround with high-quality products. The team is very knowledgeable and easy to work with. They set a high bar for what a service partner should be in the field.

Synoligo’s team was very helpful in providing solutions to the synthesis challenges I presented to them. They are highly collaborative and respond promptly. Synoligo were willing to execute complex synthesis projects that other vendors did not and have done it with great professionalism. I highly recommend choosing Synoligo as your Oligonucleotide synthesis partner.

I highly value the customer service provided by Synoligo – your expertise ensures that you can find the best option for the customer. The production time is exceptional; I received a few grams of oligo in 3 weeks or less. The combination of a wide range of available modifications, comprehensive characterization of the final product, and fast turnaround is unbeatable in today's market.

The communication from Synoligo team has always been clear and prompt. My inquiries and questions were addressed with expertise and efficiency. I felt well-informed. ​ One key aspect that sets Synoligo apart is the reliability of oligo synthesis service. The high quality and consistency of the synthesized materials have significantly contributed to the success of our research efforts. In addition, the turnaround time for the synthesis projects was impressive. Synoligo ensured that our timelines were met without compromising on the quality.

Synoligo is the only CRO I know of that will provide material in as little as 2 weeks. They are the only vendor I know of that will guarantee low endo material, even at small scale. On many projects they have functioned more as partners rather than a service provider. This has helped us with moving a number of projects forward more quickly. When time and purity are critical, Synoligo is my go-to place.

I’ve recommended Synoligo to several of my clients and some have used their services. Synoligo was able to deliver many very complicated oligonucleotides that other “oligo houses” or core labs were not able to synthesize because Synoligo has several advantages:​ 1) Access to several monomers/modifications not easy to source​ 2) Great chemical experience allowing Synoligo to develop rapidly appropriate synthesis and purification methods while de-risking the process​ 3) Very responsive​. Synoligo is also a lot more flexible than most of the other labs specialized in oligo synthesis who prefer to use what they name “best practices” that all have limitation to the most traditional Oligonucleotides. Synoligo also provides a deeper customer services because they understand customers needs more completely than most of the market. Synoligo is great in handling customer interaction to make the experience something special.