Therapeutic Development
With the emerging of targeted medicines from antisense, siRNA and CRISPR technologies, oligonucleotides play a critical role in these applications. At Synoligo, we specialize and excel in producing high-quality custom oligos tailored for numerous clients in these therapeutic arenas. Whether in the initial concept stage or the product development phase, we stand ready to meet the evolving needs of the therapeutic industry with precision and expertise.
Features & Benefits
Fully Customizable Project
Tailor to your project 100%.
Qualified Vendors and Suppliers
Certified clinical grade raw materials
Guaranteed Quality Product
High purity and consistent low endotoxin even for lipid conjugated oligos
Seamless Process Transfer
Transition your projects between different CROs & CMOs
What We Offer
Synoligo offers a wide range of customizations, with the capability to incorporate the same modifications available for DNA oligos into your desired RNA molecules.
What We Offer
Synoligo offers a wide range of customizations, with the capability to incorporate the same modifications available for DNA oligos into your desired RNA molecules.
| Types | Features |
|---|---|
| Antisense Oligonucleotides (ASOs) | Phosphothioate, fully modified gapmer or ligand conjugated |
| Aptamer | DNA-, RNA-, TNA-, or Spiegelmer®-based, PEGylated, bispecific |
| siRNA/saRNA/miRNA | Standard and novel modifications, linker modified ready for click and maleimide chemistry, or ligand conjugated |
| CRISPR/sgRNA | For Cas12a, Cas9 |
| pegRNA for prime editing up to 200mer (enzymatic ligation recommended for >150mer) | |
| Immunostimulatory agent | Including CpG1018, CpG7909, 5’-di- and 5’-triphosphate oligo with novel DNA/RNA modifications |
| Miscellaneous oligo types | Stereo defined, PMO, tRNA, DNA decoy, branched oligo, circular oligo, oligo for RNA editing |
| Oligo synthesis with dimer or trimer building blocks | |
| New chemistry screening | Work with customer proprietary chemistry |
| Process research and development | Support of GMP batch production |
| Customizable purity and low tox oligo | Deliverables come with COA including EI, RS, sodium, endotoxin, and bioburden tests |
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Applications of Oligos
With decades of experience, our expert team specializes in manufacturing oligos tailored to diverse scientific applications, ensuring your specific needs are met.
Research & Innovation
Extensive list of customization allows researchers to achieve their research goals.
Molecular Diagnostics
Broad selection of various dyes and probes.
- Branched/dendrimer
- Circular DNA/RNA
- Ultra-long oligos (150-200nt)
- DNA-encoded library (DEL)
- Primers PCR/qPCR
- FISH/MERFISH Probes
- FRET Probes
- NGS Adapters
- Molecular Beacon
Applications of Oligos
With decades of experience, our expert team specializes in manufacturing oligos tailored to diverse scientific applications, ensuring your specific needs are met.
Research & Innovation
Extensive list of customization allows researchers to achieve their research goals.
- Branched/dendrimer
- Circular DNA/RNA
- Ultra-long oligos (150-200nt)
- DNA-encoded library (DEL)
Molecular Diagnostics
Broad selection of various dyes and probes.
- Primers PCR/qPCR
- FISH/MERFISH Probes
- FRET Probes
- NGS Adapters
- Molecular Beacon